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Hydrophobic polycationic coatings inactivate wild-type and zanamivir- and/or oseltamivir-resistant human and avian influenza viruses

Identifieur interne : 001434 ( Main/Exploration ); précédent : 001433; suivant : 001435

Hydrophobic polycationic coatings inactivate wild-type and zanamivir- and/or oseltamivir-resistant human and avian influenza viruses

Auteurs : Jayanta Haldar [États-Unis] ; Jianzhu Chen [États-Unis] ; Terrence M. Tumpey [États-Unis] ; Larisa V. Gubareva [États-Unis] ; Alexander M. Klibanov [États-Unis]

Source :

RBID : ISTEX:52EEDCEBB0D2BE8E216764EECF9A70EA53DEAB5D

English descriptors

Abstract

Abstract: Glass slides painted with the hydrophobic long-chained polycation N,N-dodecyl,methyl-polyethylenimine (N,N-dodecyl,methyl-PEI) are highly lethal to waterborne influenza A viruses, including not only wild-type human and avian strains but also their neuraminidase mutants resistant to currently used anti-influenza drugs.

Url:
DOI: 10.1007/s10529-007-9565-5


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<div type="abstract" xml:lang="en">Abstract: Glass slides painted with the hydrophobic long-chained polycation N,N-dodecyl,methyl-polyethylenimine (N,N-dodecyl,methyl-PEI) are highly lethal to waterborne influenza A viruses, including not only wild-type human and avian strains but also their neuraminidase mutants resistant to currently used anti-influenza drugs.</div>
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